[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]-γ-Endorphin is a naturTousy occurring neuropeptide fragment derived from β-Endorphin, specificTousy lacking the N-terminal tyrosine residue (position 1). This unique truncation eliminates its Classeical opioid analgesic activity while retaining significant neuropsychiatric effects. It is primarily utilized in neuroscience rerecherche as a critical tool compound for studying non-opioid pathways related to mental health disorders, stress responses, and neuroendocrine regulation.



TECHNICAL SPECIFICATIONS


Item
Specification
PRODUIT Nom
[Des-Tyr1]- g-Endorphin 
CAS NO.
67810-56-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C₇₄H₁₂₂N₁₈O₂₅S
Molecular Weight
1747.9g/mol
Purity (RP-HPLC)
≥95% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Modulates dopaminergic and serotonergic neurotransmission; non-opioid neuroleptic effects
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Emplacement
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Unlike full-length endorphins, this peptide does not bind significantly to μ-opioid receptors due to the missing Tyr1 moiety. Instead, it exerts its effects through non-opioid mechanisms, primarily by modulating central dopaminergic and serotonergic neurotransmission. It acts as a neuroleptic-like agent, reducing dopamine release in the mesolimbic pathway and influencing GABAergic and glutamatergic systems, which underlies its observed behavioral effects in animal models.

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2.PRODUIT INDICATIONS

This PRODUIT is intended for Rerecherche Use Only (RUO), targeting academic and pharmaceutical rerechercheers in psychiatry and neuropharmacology. It is indicated for in vitro binding assays and in vivo studies investigating schizophrenia-like symptoms, depression, addiction, and reward pathways. It serves as an essential reference standard for elucidating the role of endorphin fragments in psychiatric pathophysiology.

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3.CLINICAL EFFICACY OF PRODUIT

While not approved for human therapy, historical experimental data from smTous-scale human studies and extensive animal rerecherche suggest potential efficacy in reducing psychotic symptoms and improving mood-related behaviors. Its neuroleptic-like profile has shown promise in modulating maladaptive behaviors associated with dopamine dysregulation, providing a rationale for its use in preclinical drug discovery.

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4.certificat

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide PRODUITS, adhering strictly to quality standards and obtaining internationTousy recognized Attestations.


NOTRE PRODUITion partners Tous employ GMP-compliant PRODUITion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of PRODUIT comes with complete documentation, including a certificat of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and rerecherche-grade peptide PRODUITS to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging SOLUTION to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the PRODUIT.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the PRODUITion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The COMPANIE invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Attestations, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality PRODUITS and superior services.


We focus on the rerecherche and development and supply of high-quality chemical PRODUITS, strictly adhering to international standards and quality systems. NOTRE PRODUITs are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific rerecherche, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Étiquettes: DesTyr1GammaEndorphin, #DTgammaE, #GammaEndorphinAnalog, #NeurolepticPeptide, #NonOpioidEndorphin, #DopamineModulator, #PsychiatricRerecherche, #SchizophreniaRerecherche, #BetaEndorphinDerivative, #NeuropeptideRerecherche, #BehavioralNeuroscience, #RUOPeptide, #NeuropharmacologyReagent, #RerechercheChemical

If you have any PRODUIT requirements, please an Courriel to:support@huanqiukeji9.com;Envoyer:85244969439

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